Biology

The modern market of the roofing materials is very wide. Choice of this or any other roofing material requires an integrated approach. Many factors should be considered. Among them design and aesthetic requirements as well as the environmental conditions of its operation and last but not least, the financial capacity of a building contractor.
2012

Discovering carcinogenic properties of asbestos in cancer epidemiology and experimental studies resulted in a tough struggle between opponents and supporters of its continued industrial use. In some cases this struggle (and opposition in the first place) gets farther away from the reality and scientific facts and often acquires a commercial and political format.
2012

Actuality. To date, assessment of the effects of the mutagen-induced production factors and the effects of environmental factors is carried out by detecting chromosomal damage by analysis of chromosomal aberrations and sister chromatid exchanges in peripheral blood lymphocytes. To evaluate the mutational event is necessary to use method of accounting for chromosomal aberrations, which is a highly sensitive methods of biological indication of human exposure to mutagens and production of environmental factors. In the molecules of DNA genetic information is encoded, mutagenic, acting on the cell, leading to breaks and rearrangements of chromosome structure [1]. In the formation of chromosomal aberrations important stage of the mitotic cell cycle, which occurred at the time of the impact of the mutagen.
2012

The article presented the state of production and use of asbestos in Kazakhstan and the EECCA region. Discussion on potential health risks of asbestos production and use, including NGO recommendation for action. According the WECF \EcoForum partnership project «Civil Society and Sound Hazardous Waste Management in Kazakhstan» and High-Level Conference «Asbestos and POPs — policies and practices in Kazakhstan and the European Union» was identify next steps and recommendations to develop a strategy on asbestos in Kazakhstan and Kazakhstan’s position regarding Rotterdam Convention. 
2012

Authors showed that interaction of diabetogenic chelators as Diphenylthiocarbazone and formed in Human some derivatives of 8-oxyquinolin with Zn2+-ions contained in B-cells result destruction of cells and develop- ing of 1 type diabetes. Preliminary elimination of Zn2+ — ion- from cells or blocking ions by not diabetogenic chelators protect B-cells of interaction with diabetogenic substances and as result — of developing of diabetes. 
2013

Authors showed new experimental data on the state of histostructure of Liver and Exocrine Pancreas tissue in experimental diabetes approached on conditions of development to human 2 type diabetes caused by 4,8-dihydroxyquinolin-2-carboxylic acid — the substance actively synthesized in elderly human, unlike all known today more than 30 diabetogenic substances. It is established that, at the same time with destruction of pancreatic B-cells that is a direct cause of diabetes, a multiple destructive changes are developed in a Liver and in Exocrine tissue of Pancreas. Authors suppose these changes which are not belong to direct causes of developed diabetes, but can aggravate diabetes considerably.
2013

A tissue culture experimental model is best for to study the direct effect of diabetogenic chemicals not possible products of its metabolisation on pancreatic B-cells. Authors are adopted to tissue culture model of isolated pancreatic islets histological and histochemical methods analysis of histostructure of islets and of insulin content in B-cells. The high quality results of analysis of histostructure of islets were obtained using Aldehydefuchsine method and most precise results of estimation of insulin content in B-cells by using of fluorescent Pseudoisocyanine and Immunofluorescent methods.
2013

Authors showed that almost complete elimination of zinc-insulin complex from cytoplasm of B-cells caused   by 3 days prolonged administration of Glibenclamide to animals accompanied by complete disappearing of insulin and zinc-ions from B-cells. Next 6–7 days free of using of Glibenclamide result parallel complete recovery of amount of insulin and zinc in B-cells without any changes of histostructure of islets and function of B-cells.
2013

Authors demonstrated results using of high specific fluorescent method histochemical staining of Zn+2-ions in pancreatic B-cells. It was showed in diabetic animals and in animals past mobilization of insulin from B-cells a simultaneous decreasing as of amount of insulin as of Zn+2-ions in cytoplasm of B-cells. Meanwhile for- mation in B-cells of chemical complexes of derivatives of Diethyldithiocarbamic acid with Zn+2-ions result negative fluorescent reaction for Zn+2-ions but positive reaction for insulin using of insulin staining methods.
2013

Risk developing of a stroke in patients with diabetes 2.8 times is higher comparatively with health persons. Authors proposed the mathematical model «stroke-risk factors» for definition probability of developing of stroke at patients with diabetes 2 types based on standard methods carried out in medical service. The analysis of mathematical model allowed to establish the speed of increase of a stroke for urgent hospitalization of patients.
2013

At patients diabetes 2 types noted the high frequency of bezbolevy ischemia of a myocardium (17,4 %), atypical symptoms of coronary heart disease (59,4 %), chronic warm insufficiency (60,9 %) and early development of coronary heart disease (63,8 %). Risk factors of development of coronary heart disease at patients with diabetes 2 types are the long course of diabetes, an arterial hypertension, a heavy decompensation of a carbohydrate exchange, violation of the lipidic exchange, the raised level of uric acid.
2013

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Philology is the study of language in oral and written historical sources; it is the intersection between textual criticism, literary criticism, history, and linguistics.[

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